Load Specifications
Load data in caliber .375 Ruger with .376 | 256gr | Peregrine VLR-5 bullet and 94 powders. The key underlying parameters are shown in the table above. The recommended powders for this cartridge and bullet combination are Alliant Power Pro 2000-MR, ReloadSwiss RS 52 and ReloadSwiss RS 60.
Important Notice: DO NOT go below Minimum Charge or above Maximum Charge. Since we have no control over the equipment and components used, any responsibility and liability for the results achieved is rejected.
Only powders/loads that match the current filter criteria are displayed: max pressure of a load ≤ 90% of max. standardized pressure, fill rate ≥ 80% and propellant combustion ≥ 95%. Use the sliders above the tables to adjust these thresholds.
Charge: Powder weight in grains. Start with the minimum load and work up carefully.
FR (Fill Rate): Case fill as a percentage. Values above 100% mean compressed loads.
MaxP / %: Maximum chamber pressure in bar and as a percentage of the standardized maximum for this caliber.
V(0): Muzzle velocity in feet per second (fps) at the standardized barrel length.
z (Powder Burn): Estimated propellant combustion percentage at bullet exit.
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You can find more information in our FAQ: How can I use the Personalized Load Calculator?
Max Load - Barrel Length: 23"
| Powder | Charge | FR | MaxP | % | V(0) | z |
|---|---|---|---|---|---|---|
| Accurate 2015 | <<locked>> | 88% | 52,576 psi | 85% | 2503 fps | 100% |
| Accurate 2460 | <<locked>> | 86% | 54,636 psi | 88% | 2569 fps | 100% |
| Accurate 2495 | <<locked>> | 94% | 53,026 psi | 85% | 2552 fps | 100% |
| Accurate 2520 | <<locked>> | 88% | 52,533 psi | 85% | 2575 fps | 100% |
| Accurate 4064 | <<locked>> | 96% | 52,910 psi | 85% | 2592 fps | 100% |
| Accurate 4350ᴾ | <<locked>> | 100% | 45,295 psi | 73% | 2543 fps | 97.4% |
| Accurate LT-30 | <<locked>> | 84% | 56,115 psi | 90% | 2500 fps | 100% |
| Accurate LT-32 | <<locked>> | 82% | 53,229 psi | 86% | 2480 fps | 100% |
| ADI AR 2206H | <<locked>> | 92% | 55,419 psi | 89% | 2631 fps | 99.6% |
| ADI AR 2208 | <<locked>> | 96% | 52,866 psi | 85% | 2575 fps | 99% |
| ADI AR 2219 | <<locked>> | 82% | 53,142 psi | 86% | 2562 fps | 100% |
| ADI Benchmark 8208 | <<locked>> | 90% | 54,708 psi | 88% | 2592 fps | 99.9% |
| Alliant AR-Comp | <<locked>> | 90% | 54,346 psi | 88% | 2572 fps | 100% |
| Alliant Power Pro 1200-R | <<locked>> | 86% | 56,173 psi | 90% | 2687 fps | 99.9% |
| Alliant Power Pro 2000-MR | <<locked>> | 94% | 54,969 psi | 89% | 2730 fps | 99.3% |
| Alliant Reloder- TS 15.5 | <<locked>> | 98% | 55,419 psi | 89% | 2641 fps | 99.9% |
| Alliant Reloder-10x | <<locked>> | 86% | 55,999 psi | 90% | 2552 fps | 100% |
| Alliant Reloder-15 | <<locked>> | 94% | 52,794 psi | 85% | 2612 fps | 99.1% |
| Alliant Reloder-16ᴾ | <<locked>> | 100% | 45,556 psi | 73% | 2556 fps | 97.5% |
| Alliant Reloder-17ᴾ | <<locked>> | 100% | 52,634 psi | 85% | 2697 fps | 99.8% |
| Baschieri & Pellagri 106 | <<locked>> | 84% | 55,448 psi | 89% | 2497 fps | 100% |
| Baschieri & Pellagri 107 | <<locked>> | 92% | 55,100 psi | 89% | 2638 fps | 99% |
| Bofors RP3 | <<locked>> | 98% | 55,883 psi | 90% | 2654 fps | 99.9% |
| Hodgdon Benchmark | <<locked>> | 88% | 53,476 psi | 86% | 2536 fps | 100% |
| Hodgdon BL-C2 | <<locked>> | 90% | 53,345 psi | 86% | 2612 fps | 100% |
| Hodgdon CFE223 | <<locked>> | 88% | 55,419 psi | 89% | 2703 fps | 99.4% |
| Hodgdon H322 | <<locked>> | 86% | 55,347 psi | 89% | 2592 fps | 100% |
| Hodgdon H335 | <<locked>> | 84% | 52,939 psi | 85% | 2569 fps | 100% |
| Hodgdon H380 | <<locked>> | 96% | 53,940 psi | 87% | 2615 fps | 98.3% |
| Hodgdon H4895 | <<locked>> | 92% | 55,898 psi | 90% | 2641 fps | 99.8% |
| Hodgdon Hybrid 100Vᴾ | <<locked>> | 100% | 41,510 psi | 67% | 2448 fps | 98.1% |
| Hodgdon LEVERevolution | <<locked>> | 94% | 54,447 psi | 88% | 2664 fps | 99.9% |
| Hodgdon TrailBossᴾ | <<locked>> | 100% | 34,418 psi | 55% | 1572 fps | 100% |
| Hodgdon VARGET | <<locked>> | 92% | 53,838 psi | 87% | 2595 fps | 99.7% |
| IMR 3031 | <<locked>> | 92% | 55,129 psi | 89% | 2628 fps | 100% |
| IMR 4064 | <<locked>> | 96% | 55,709 psi | 90% | 2605 fps | 99.4% |
| IMR 4166 Enduron | <<locked>> | 92% | 53,156 psi | 86% | 2539 fps | 96% |
| IMR 4198 | <<locked>> | 84% | 53,345 psi | 86% | 2480 fps | 100% |
| IMR 4451 Enduronᴾ | <<locked>> | 100% | 55,651 psi | 90% | 2605 fps | 96.4% |
| IMR 4831ᴾ | <<locked>> | 100% | 43,395 psi | 70% | 2493 fps | 97% |
| IMR 4895 | <<locked>> | 94% | 54,157 psi | 87% | 2641 fps | 99.6% |
| IMR 8208 XBR | <<locked>> | 90% | 54,708 psi | 88% | 2592 fps | 99.9% |
| Lovex D073.5 | <<locked>> | 86% | 54,505 psi | 88% | 2575 fps | 100% |
| Lovex D073.6 | <<locked>> | 92% | 54,215 psi | 87% | 2605 fps | 100% |
| Lovex S060 | <<locked>> | 92% | 55,579 psi | 90% | 2566 fps | 99.6% |
| Lovex S062 | <<locked>> | 96% | 55,013 psi | 89% | 2605 fps | 100% |
| Lovex S065ᴾ | <<locked>> | 100% | 50,807 psi | 82% | 2543 fps | 97% |
| Norma 200 | <<locked>> | 82% | 55,622 psi | 90% | 2526 fps | 100% |
| Norma 201 | <<locked>> | 92% | 53,882 psi | 87% | 2579 fps | 99.9% |
| Norma 202 | <<locked>> | 92% | 54,215 psi | 87% | 2585 fps | 100% |
| Norma 203B | <<locked>> | 96% | 55,405 psi | 89% | 2648 fps | 99.6% |
| Norma URPᴾ | <<locked>> | 100% | 45,556 psi | 73% | 2539 fps | 97.3% |
| Ramshot Big Game | <<locked>> | 94% | 52,489 psi | 85% | 2625 fps | 99.3% |
| Ramshot TAC | <<locked>> | 90% | 55,376 psi | 89% | 2602 fps | 98% |
| Ramshot Wild Boar | <<locked>> | 90% | 54,288 psi | 87% | 2618 fps | 99.5% |
| Ramshot X-Terminator | <<locked>> | 88% | 56,144 psi | 90% | 2592 fps | 99.5% |
| ReloadSwiss RS 14ᴾ | <<locked>> | 100% | 34,679 psi | 56% | 1608 fps | 100% |
| ReloadSwiss RS 40 | <<locked>> | 86% | 54,491 psi | 88% | 2579 fps | 100% |
| ReloadSwiss RS 50 | <<locked>> | 96% | 54,723 psi | 88% | 2598 fps | 97% |
| ReloadSwiss RS 52 | <<locked>> | 92% | 52,765 psi | 85% | 2674 fps | 99.1% |
| ReloadSwiss RS 60 | <<locked>> | 98% | 52,707 psi | 85% | 2703 fps | 100% |
| ReloadSwiss RS 62ᴾ | <<locked>> | 100% | 45,179 psi | 73% | 2559 fps | 97% |
| ReloadSwiss RS 70ᴾ | <<locked>> | 100% | 46,543 psi | 75% | 2579 fps | 96.4% |
| Rottweil R 901 | <<locked>> | 90% | 54,563 psi | 88% | 2566 fps | 100% |
| Rottweil R 902 | <<locked>> | 94% | 54,085 psi | 87% | 2572 fps | 99.9% |
| Rottweil R 903ᴾ | <<locked>> | 100% | 55,506 psi | 89% | 2641 fps | 99.9% |
| Shooters World Long Rifleᴾ | <<locked>> | 100% | 50,807 psi | 82% | 2543 fps | 97% |
| Shooters World Match Rifle | <<locked>> | 92% | 54,215 psi | 87% | 2605 fps | 100% |
| Shooters World Precision | <<locked>> | 96% | 55,013 psi | 89% | 2605 fps | 100% |
| Shooters World Tactical Rifle | <<locked>> | 84% | 54,317 psi | 88% | 2549 fps | 99.8% |
| SNPE Vectan SP 10 | <<locked>> | 82% | 53,519 psi | 86% | 2572 fps | 100% |
| SNPE Vectan SP 11 | <<locked>> | 98% | 54,157 psi | 87% | 2654 fps | 99.5% |
| SNPE Vectan SP 3 | <<locked>> | 84% | 53,650 psi | 86% | 2533 fps | 100% |
| SNPE Vectan SP 7 | <<locked>> | 90% | 53,069 psi | 85% | 2572 fps | 98.1% |
| SNPE Vectan SP 9 | <<locked>> | 92% | 53,766 psi | 87% | 2602 fps | 99.5% |
| SNPE Vectan Tubal 3000 | <<locked>> | 92% | 56,072 psi | 90% | 2530 fps | 100% |
| SNPE Vectan Tubal 5000 | <<locked>> | 98% | 55,985 psi | 90% | 2526 fps | 100% |
| Somchem S321 | <<locked>> | 88% | 56,101 psi | 90% | 2625 fps | 100% |
| Somchem S335 | <<locked>> | 92% | 55,143 psi | 89% | 2530 fps | 100% |
| Somchem S341 | <<locked>> | 90% | 52,837 psi | 85% | 2572 fps | 99.3% |
| Somchem S355ᴾ | <<locked>> | 100% | 56,173 psi | 90% | 2641 fps | 99.8% |
| Somchem S365ᴾ | <<locked>> | 100% | 40,422 psi | 65% | 2493 fps | 99.1% |
| Vihtavuori N130 | <<locked>> | 88% | 55,883 psi | 90% | 2503 fps | 100% |
| Vihtavuori N133 | <<locked>> | 92% | 56,057 psi | 90% | 2520 fps | 100% |
| Vihtavuori N135 | <<locked>> | 94% | 53,214 psi | 86% | 2549 fps | 100% |
| Vihtavuori N140 | <<locked>> | 94% | 54,926 psi | 88% | 2566 fps | 100% |
| Vihtavuori N150ᴾ | <<locked>> | 100% | 54,389 psi | 88% | 2582 fps | 100% |
| Vihtavuori N160ᴾ | <<locked>> | 100% | 48,080 psi | 77% | 2543 fps | 97.7% |
| Vihtavuori N530 | <<locked>> | 90% | 55,245 psi | 89% | 2589 fps | 100% |
| Vihtavuori N540 | <<locked>> | 94% | 53,171 psi | 86% | 2562 fps | 100% |
| Vihtavuori N550ᴾ | <<locked>> | 100% | 47,050 psi | 76% | 2546 fps | 97.3% |
| Winchester 6.5 StaBALLᴾ | <<locked>> | 100% | 49,356 psi | 80% | 2533 fps | 99.4% |
| Winchester 748 | <<locked>> | 90% | 54,520 psi | 88% | 2631 fps | 100% |
| Winchester StaBALL Match | <<locked>> | 92% | 53,490 psi | 86% | 2608 fps | 99.7% |
Recommended = one of the top powders for this cartridge and bullet combination.
Start Load - Barrel Length: 23"
| Powder | Charge | FR | MaxP | % | V(0) | z |
|---|---|---|---|---|---|---|
| Accurate 2015 | <<locked>> | 80% | 40,915 psi | 66% | 2336 fps | 100% |
| Accurate 2460 | <<locked>> | 80% | 44,382 psi | 71% | 2425 fps | 99.9% |
| Accurate 2495 | <<locked>> | 80% | 32,982 psi | 53% | 2247 fps | 100% |
| Accurate 2520 | <<locked>> | 80% | 39,726 psi | 64% | 2382 fps | 99.5% |
| Accurate 4064 | <<locked>> | 80% | 31,241 psi | 50% | 2228 fps | 98.6% |
| Accurate 4350 | <<locked>> | 96% | 39,131 psi | 63% | 2438 fps | 95.8% |
| Accurate LT-30 | <<locked>> | 80% | 49,748 psi | 80% | 2418 fps | 100% |
| Accurate LT-32 | <<locked>> | 80% | 50,125 psi | 81% | 2438 fps | 100% |
| ADI AR 2206H | <<locked>> | 80% | 37,666 psi | 61% | 2339 fps | 96.6% |
| ADI AR 2208 | <<locked>> | 84% | 36,390 psi | 59% | 2297 fps | 95.3% |
| ADI AR 2219 | <<locked>> | 80% | 49,719 psi | 80% | 2520 fps | 100% |
| ADI Benchmark 8208 | <<locked>> | 80% | 39,755 psi | 64% | 2359 fps | 98.3% |
| Alliant AR-Comp | <<locked>> | 80% | 38,580 psi | 62% | 2359 fps | 100% |
| Alliant Power Pro 1200-R | <<locked>> | 80% | 46,021 psi | 74% | 2536 fps | 99% |
| Alliant Power Pro 2000-MR | 66.4 gr | 84% | 38,928 psi | 63% | 2451 fps | 95.7% |
| Alliant Reloder- TS 15.5 | <<locked>> | 80% | 30,908 psi | 50% | 2215 fps | 95.3% |
| Alliant Reloder-10x | <<locked>> | 80% | 46,441 psi | 75% | 2428 fps | 100% |
| Alliant Reloder-15 | <<locked>> | 82% | 35,723 psi | 58% | 2320 fps | 95.4% |
| Alliant Reloder-16 | <<locked>> | 94% | 37,710 psi | 61% | 2402 fps | 95% |
| Alliant Reloder-17 | <<locked>> | 86% | 32,721 psi | 53% | 2316 fps | 95% |
| Baschieri & Pellagri 106 | <<locked>> | 80% | 48,689 psi | 78% | 2411 fps | 100% |
| Baschieri & Pellagri 107 | <<locked>> | 82% | 39,247 psi | 63% | 2385 fps | 95.8% |
| Bofors RP3 | <<locked>> | 80% | 30,037 psi | 48% | 2208 fps | 95.1% |
| Hodgdon Benchmark | <<locked>> | 80% | 41,684 psi | 67% | 2352 fps | 99% |
| Hodgdon BL-C2 | <<locked>> | 80% | 37,637 psi | 61% | 2362 fps | 98.4% |
| Hodgdon CFE223 | <<locked>> | 80% | 41,524 psi | 67% | 2484 fps | 97.1% |
| Hodgdon H322 | <<locked>> | 80% | 45,382 psi | 73% | 2457 fps | 100% |
| Hodgdon H335 | <<locked>> | 80% | 46,050 psi | 74% | 2474 fps | 100% |
| Hodgdon H380 | <<locked>> | 88% | 41,118 psi | 66% | 2415 fps | 95.6% |
| Hodgdon H4895 | <<locked>> | 80% | 37,956 psi | 61% | 2352 fps | 97.3% |
| Hodgdon Hybrid 100V | <<locked>> | 94% | 34,272 psi | 55% | 2303 fps | 95.8% |
| Hodgdon LEVERevolution | <<locked>> | 80% | 33,852 psi | 55% | 2310 fps | 96.4% |
| Hodgdon TrailBoss | <<locked>> | 80% | 25,469 psi | 41% | 1404 fps | 100% |
| Hodgdon VARGET | <<locked>> | 80% | 36,608 psi | 59% | 2310 fps | 96.8% |
| IMR 3031 | <<locked>> | 80% | 36,840 psi | 59% | 2359 fps | 100% |
| IMR 4064 | <<locked>> | 82% | 35,665 psi | 57% | 2277 fps | 95.4% |
| IMR 4166 Enduron | <<locked>> | 90% | 49,879 psi | 80% | 2490 fps | 95.2% |
| IMR 4198 | <<locked>> | 80% | 47,253 psi | 76% | 2402 fps | 100% |
| IMR 4451 Enduron | <<locked>> | 98% | 52,185 psi | 84% | 2556 fps | 95.7% |
| IMR 4831 | <<locked>> | 96% | 38,000 psi | 61% | 2395 fps | 95.4% |
| IMR 4895 | <<locked>> | 80% | 34,345 psi | 55% | 2300 fps | 95.6% |
| IMR 8208 XBR | <<locked>> | 80% | 39,755 psi | 64% | 2359 fps | 98.3% |
| Lovex D073.5 | <<locked>> | 80% | 44,295 psi | 71% | 2431 fps | 99.6% |
| Lovex D073.6 | <<locked>> | 80% | 35,839 psi | 58% | 2320 fps | 98.9% |
| Lovex S060 | <<locked>> | 80% | 38,363 psi | 62% | 2290 fps | 96.8% |
| Lovex S062 | <<locked>> | 80% | 33,011 psi | 53% | 2234 fps | 96.6% |
| Lovex S065 | <<locked>> | 96% | 44,860 psi | 72% | 2451 fps | 95.6% |
| Norma 200 | <<locked>> | 80% | 52,344 psi | 84% | 2487 fps | 100% |
| Norma 201 | <<locked>> | 80% | 36,753 psi | 59% | 2300 fps | 97.7% |
| Norma 202 | <<locked>> | 80% | 36,869 psi | 59% | 2316 fps | 99.4% |
| Norma 203B | <<locked>> | 80% | 32,938 psi | 53% | 2260 fps | 95% |
| Norma URP | <<locked>> | 96% | 39,813 psi | 64% | 2438 fps | 95.7% |
| Ramshot Big Game | <<locked>> | 82% | 34,737 psi | 56% | 2316 fps | 95.3% |
| Ramshot TAC | <<locked>> | 82% | 42,395 psi | 68% | 2398 fps | 95.1% |
| Ramshot Wild Boar | <<locked>> | 80% | 38,624 psi | 62% | 2365 fps | 96.8% |
| Ramshot X-Terminator | <<locked>> | 80% | 43,149 psi | 70% | 2398 fps | 97.8% |
| ReloadSwiss RS 14 | <<locked>> | 80% | 25,643 psi | 41% | 1437 fps | 100% |
| ReloadSwiss RS 40 | <<locked>> | 80% | 44,585 psi | 72% | 2438 fps | 99.8% |
| ReloadSwiss RS 50 | <<locked>> | 92% | 47,892 psi | 77% | 2497 fps | 95.5% |
| ReloadSwiss RS 52 | 62.8 gr | 82% | 36,999 psi | 60% | 2405 fps | 95.8% |
| ReloadSwiss RS 60 | 62.3 gr | 80% | 28,645 psi | 46% | 2221 fps | 95.7% |
| ReloadSwiss RS 62 | <<locked>> | 96% | 39,334 psi | 63% | 2454 fps | 95.3% |
| ReloadSwiss RS 70 | <<locked>> | 98% | 43,410 psi | 70% | 2520 fps | 95.5% |
| Rottweil R 901 | <<locked>> | 80% | 40,277 psi | 65% | 2349 fps | 99.7% |
| Rottweil R 902 | <<locked>> | 80% | 34,824 psi | 56% | 2254 fps | 97.1% |
| Rottweil R 903 | <<locked>> | 84% | 32,285 psi | 52% | 2254 fps | 95.6% |
| Shooters World Long Rifle | <<locked>> | 96% | 44,860 psi | 72% | 2451 fps | 95.6% |
| Shooters World Match Rifle | <<locked>> | 80% | 35,839 psi | 58% | 2320 fps | 98.9% |
| Shooters World Precision | <<locked>> | 80% | 33,011 psi | 53% | 2234 fps | 96.6% |
| Shooters World Tactical Rifle | <<locked>> | 80% | 47,224 psi | 76% | 2451 fps | 99.2% |
| SNPE Vectan SP 10 | <<locked>> | 80% | 49,980 psi | 81% | 2526 fps | 100% |
| SNPE Vectan SP 11 | <<locked>> | 84% | 34,011 psi | 55% | 2306 fps | 95.1% |
| SNPE Vectan SP 3 | <<locked>> | 80% | 47,239 psi | 76% | 2448 fps | 100% |
| SNPE Vectan SP 7 | <<locked>> | 82% | 40,205 psi | 65% | 2369 fps | 95.1% |
| SNPE Vectan SP 9 | <<locked>> | 80% | 36,230 psi | 58% | 2310 fps | 96.1% |
| SNPE Vectan Tubal 3000 | <<locked>> | 80% | 38,450 psi | 62% | 2274 fps | 99.5% |
| SNPE Vectan Tubal 5000 | <<locked>> | 80% | 31,473 psi | 51% | 2149 fps | 99.1% |
| Somchem S321 | <<locked>> | 80% | 42,583 psi | 69% | 2425 fps | 99.1% |
| Somchem S335 | <<locked>> | 80% | 37,985 psi | 61% | 2277 fps | 99.8% |
| Somchem S341 | <<locked>> | 80% | 37,246 psi | 60% | 2320 fps | 96.3% |
| Somchem S355 | <<locked>> | 82% | 31,430 psi | 51% | 2218 fps | 95% |
| Somchem S365 | <<locked>> | 90% | 29,138 psi | 47% | 2238 fps | 95.2% |
| Vihtavuori N130 | <<locked>> | 80% | 43,743 psi | 70% | 2346 fps | 100% |
| Vihtavuori N133 | <<locked>> | 80% | 38,624 psi | 62% | 2277 fps | 100% |
| Vihtavuori N135 | <<locked>> | 80% | 33,736 psi | 54% | 2254 fps | 100% |
| Vihtavuori N140 | <<locked>> | 80% | 34,809 psi | 56% | 2257 fps | 99.3% |
| Vihtavuori N150 | <<locked>> | 80% | 27,876 psi | 45% | 2116 fps | 95.1% |
| Vihtavuori N160 | <<locked>> | 94% | 39,334 psi | 63% | 2395 fps | 95.4% |
| Vihtavuori N530 | <<locked>> | 80% | 39,552 psi | 64% | 2349 fps | 98.3% |
| Vihtavuori N540 | <<locked>> | 80% | 33,388 psi | 54% | 2241 fps | 98.7% |
| Vihtavuori N550 | <<locked>> | 94% | 38,537 psi | 62% | 2398 fps | 95% |
| Winchester 6.5 StaBALL | <<locked>> | 88% | 33,011 psi | 53% | 2234 fps | 95.3% |
| Winchester 748 | <<locked>> | 80% | 38,450 psi | 62% | 2382 fps | 98.8% |
| Winchester StaBALL Match | <<locked>> | 80% | 35,346 psi | 57% | 2310 fps | 96.5% |
Recommended = one of the top powders for this cartridge and bullet combination.
ᴾ possible press load - work up slowly to this load while watching for signs of excessive pressure.
This overview compares 94 powders for .375 Ruger loaded with the .376 | 256gr | Peregrine VLR-5. Alliant Power Pro 2000-MR delivers the highest muzzle velocity at 2,730 fps; across all powders the maximum-charge window runs from 1,572 fps to 2,730 fps. Accurate 4350 gives the best case fill at 100 %, and 94 of the 94 powders fall inside the usable 80–100 % fill window.
Relative to the caliber's maximum pressure (428 MPa), the top charges use 55–90 %, leaving at least 10 % headroom. The 256.0 gr projectile in 0.376" calls for a 1:16.0 twist; slower twists will usually not stabilise this weight. Accurate 4350, Alliant Reloder-16, Alliant Reloder-17 reach 100 % fill or more at maximum charge, so these are compressed loads: they need a long drop tube to seat cleanly and react sensitively to the case capacity of your own brass lot. Alliant Power Pro 2000-MR, ReloadSwiss RS 52, ReloadSwiss RS 60 rank at the top here: for .375 Ruger with the .376 | 256gr | Peregrine VLR-5 they combine a high case fill with complete burn and sit in the upper velocity band. Always begin at the start load and work up in small increments while checking case and primer for pressure signs.