Load Specifications
Load data in caliber .375 Ruger with .375 | 300gr | Hornady InterBond RN bullet and 98 powders. The key underlying parameters are shown in the table above. The recommended powders for this cartridge and bullet combination are Alliant Power Pro 2000-MR, Hodgdon Superformance and Alliant Reloder-17.
Important Notice: DO NOT go below Minimum Charge or above Maximum Charge. Since we have no control over the equipment and components used, any responsibility and liability for the results achieved is rejected.
Only powders/loads that match the current filter criteria are displayed: max pressure of a load ≤ 90% of max. standardized pressure, fill rate ≥ 80% and propellant combustion ≥ 95%. Use the sliders above the tables to adjust these thresholds.
Charge: Powder weight in grains. Start with the minimum load and work up carefully.
FR (Fill Rate): Case fill as a percentage. Values above 100% mean compressed loads.
MaxP / %: Maximum chamber pressure in bar and as a percentage of the standardized maximum for this caliber.
V(0): Muzzle velocity in feet per second (fps) at the standardized barrel length.
z (Powder Burn): Estimated propellant combustion percentage at bullet exit.
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Max Load - Barrel Length: 23"
| Powder | Charge | FR | MaxP | % | V(0) | z |
|---|---|---|---|---|---|---|
| Accurate 2015 | <<locked>> | 84% | 55,143 psi | 89% | 2339 fps | 100% |
| Accurate 2495 | <<locked>> | 88% | 53,534 psi | 86% | 2359 fps | 100% |
| Accurate 2520 | <<locked>> | 84% | 55,303 psi | 89% | 2418 fps | 100% |
| Accurate 2700 | <<locked>> | 88% | 52,779 psi | 85% | 2362 fps | 97.2% |
| Accurate 3100ᴾ | <<locked>> | 100% | 40,524 psi | 65% | 2274 fps | 96.4% |
| Accurate 4064 | <<locked>> | 90% | 53,606 psi | 86% | 2402 fps | 100% |
| Accurate 4350 | <<locked>> | 98% | 53,142 psi | 86% | 2477 fps | 99.8% |
| ADI AR 2206H | <<locked>> | 86% | 54,143 psi | 87% | 2431 fps | 100% |
| ADI AR 2208 | <<locked>> | 92% | 55,114 psi | 89% | 2431 fps | 99.9% |
| ADI Benchmark 8208 | <<locked>> | 84% | 53,040 psi | 85% | 2385 fps | 100% |
| Alliant AR-Comp | <<locked>> | 84% | 53,983 psi | 87% | 2362 fps | 100% |
| Alliant Power Pro 2000-MR | <<locked>> | 88% | 53,606 psi | 86% | 2533 fps | 100% |
| Alliant Reloder- TS 15.5 | <<locked>> | 92% | 55,027 psi | 89% | 2448 fps | 100% |
| Alliant Reloder-15 | <<locked>> | 90% | 55,593 psi | 90% | 2467 fps | 100% |
| Alliant Reloder-16ᴾ | <<locked>> | 100% | 54,360 psi | 88% | 2523 fps | 99.9% |
| Alliant Reloder-17 | <<locked>> | 96% | 55,854 psi | 90% | 2556 fps | 100% |
| Alliant Reloder-23ᴾ | <<locked>> | 100% | 38,986 psi | 63% | 2303 fps | 99.2% |
| Alliant Reloder-26ᴾ | <<locked>> | 100% | 43,337 psi | 70% | 2438 fps | 98.5% |
| Baschieri & Pellagri 107 | <<locked>> | 86% | 53,867 psi | 87% | 2444 fps | 99.8% |
| Bofors RP3 | <<locked>> | 92% | 55,666 psi | 90% | 2464 fps | 100% |
| Bofors RP7 | <<locked>> | 96% | 55,680 psi | 90% | 2438 fps | 97.9% |
| Hodgdon Benchmark | <<locked>> | 84% | 54,911 psi | 88% | 2372 fps | 100% |
| Hodgdon BL-C2 | <<locked>> | 86% | 55,854 psi | 90% | 2457 fps | 100% |
| Hodgdon CFE223 | <<locked>> | 82% | 54,288 psi | 87% | 2500 fps | 100% |
| Hodgdon H380 | <<locked>> | 90% | 53,069 psi | 85% | 2428 fps | 99.5% |
| Hodgdon H414 | <<locked>> | 96% | 52,504 psi | 85% | 2474 fps | 98.1% |
| Hodgdon H4350 | <<locked>> | 94% | 53,272 psi | 86% | 2441 fps | 96.9% |
| Hodgdon H4895 | <<locked>> | 86% | 54,723 psi | 88% | 2438 fps | 100% |
| Hodgdon Hybrid 100Vᴾ | <<locked>> | 100% | 50,633 psi | 82% | 2415 fps | 100% |
| Hodgdon LEVERevolution | <<locked>> | 88% | 53,998 psi | 87% | 2467 fps | 100% |
| Hodgdon Superformance | <<locked>> | 96% | 52,939 psi | 85% | 2500 fps | 97.8% |
| Hodgdon TrailBossᴾ | <<locked>> | 100% | 35,607 psi | 57% | 1473 fps | 100% |
| Hodgdon VARGET | <<locked>> | 88% | 55,927 psi | 90% | 2441 fps | 100% |
| IMR 3031 | <<locked>> | 86% | 54,679 psi | 88% | 2421 fps | 100% |
| IMR 4064 | <<locked>> | 90% | 54,592 psi | 88% | 2415 fps | 100% |
| IMR 4166 Enduron | <<locked>> | 88% | 54,476 psi | 88% | 2398 fps | 98.2% |
| IMR 4350ᴾ | <<locked>> | 100% | 55,869 psi | 90% | 2461 fps | 98% |
| IMR 4451 Enduron | <<locked>> | 94% | 54,244 psi | 87% | 2421 fps | 98.1% |
| IMR 4831ᴾ | <<locked>> | 100% | 53,635 psi | 86% | 2467 fps | 99.8% |
| IMR 4895 | <<locked>> | 88% | 53,577 psi | 86% | 2451 fps | 100% |
| IMR 8208 XBR | <<locked>> | 84% | 53,040 psi | 85% | 2385 fps | 100% |
| Lovex D073.6 | <<locked>> | 86% | 53,853 psi | 87% | 2408 fps | 100% |
| Lovex S060 | <<locked>> | 86% | 53,722 psi | 87% | 2369 fps | 100% |
| Lovex S062 | <<locked>> | 90% | 54,534 psi | 88% | 2411 fps | 100% |
| Lovex S065 | <<locked>> | 96% | 53,592 psi | 86% | 2415 fps | 99.1% |
| Lovex S070 | <<locked>> | 98% | 54,418 psi | 88% | 2444 fps | 98.4% |
| Norma 201 | <<locked>> | 86% | 52,808 psi | 85% | 2382 fps | 100% |
| Norma 202 | <<locked>> | 86% | 53,388 psi | 86% | 2385 fps | 100% |
| Norma 203B | <<locked>> | 90% | 54,752 psi | 88% | 2457 fps | 100% |
| Norma 204 | <<locked>> | 98% | 52,881 psi | 85% | 2454 fps | 96.3% |
| Norma URPᴾ | <<locked>> | 100% | 55,753 psi | 90% | 2510 fps | 99.9% |
| Ramshot Big Game | <<locked>> | 90% | 55,419 psi | 89% | 2480 fps | 100% |
| Ramshot Hunterᴾ | <<locked>> | 100% | 54,520 psi | 88% | 2507 fps | 99% |
| Ramshot TAC | <<locked>> | 84% | 53,388 psi | 86% | 2405 fps | 99.1% |
| Ramshot Wild Boar | <<locked>> | 84% | 52,837 psi | 85% | 2418 fps | 100% |
| Ramshot X-Terminator | <<locked>> | 82% | 53,838 psi | 87% | 2388 fps | 100% |
| ReloadSwiss RS 14ᴾ | <<locked>> | 100% | 35,897 psi | 58% | 1506 fps | 100% |
| ReloadSwiss RS 40 | <<locked>> | 82% | 55,883 psi | 90% | 2408 fps | 100% |
| ReloadSwiss RS 50 | <<locked>> | 90% | 53,461 psi | 86% | 2415 fps | 98.6% |
| ReloadSwiss RS 52 | <<locked>> | 86% | 52,431 psi | 84% | 2480 fps | 99.9% |
| ReloadSwiss RS 60 | <<locked>> | 94% | 55,593 psi | 90% | 2556 fps | 100% |
| ReloadSwiss RS 62 | <<locked>> | 98% | 52,808 psi | 85% | 2497 fps | 99.6% |
| ReloadSwiss RS 70 | <<locked>> | 98% | 52,576 psi | 85% | 2520 fps | 99.5% |
| Rottweil R 901 | <<locked>> | 84% | 54,099 psi | 87% | 2365 fps | 100% |
| Rottweil R 902 | <<locked>> | 88% | 53,461 psi | 86% | 2382 fps | 100% |
| Rottweil R 903 | <<locked>> | 94% | 55,506 psi | 89% | 2454 fps | 100% |
| Rottweil R 907 | <<locked>> | 96% | 55,680 psi | 90% | 2438 fps | 97.9% |
| Shooters World Long Rifle | <<locked>> | 96% | 53,592 psi | 86% | 2415 fps | 99.1% |
| Shooters World Match Rifle | <<locked>> | 86% | 53,853 psi | 87% | 2408 fps | 100% |
| Shooters World Precision | <<locked>> | 90% | 54,534 psi | 88% | 2411 fps | 100% |
| Shooters World SW4350 | <<locked>> | 98% | 54,418 psi | 88% | 2444 fps | 98.4% |
| SNPE Vectan SP 11 | <<locked>> | 92% | 53,563 psi | 86% | 2464 fps | 100% |
| SNPE Vectan SP 7 | <<locked>> | 86% | 55,216 psi | 89% | 2431 fps | 99.6% |
| SNPE Vectan SP 9 | <<locked>> | 88% | 55,956 psi | 90% | 2451 fps | 100% |
| SNPE Vectan Tubal 3000 | <<locked>> | 86% | 54,433 psi | 88% | 2329 fps | 100% |
| SNPE Vectan Tubal 5000 | <<locked>> | 92% | 54,476 psi | 88% | 2326 fps | 100% |
| SNPE Vectan Tubal 7000 | <<locked>> | 96% | 53,708 psi | 87% | 2372 fps | 98.1% |
| Somchem S321 | <<locked>> | 82% | 54,244 psi | 87% | 2415 fps | 100% |
| Somchem S335 | <<locked>> | 86% | 53,708 psi | 87% | 2326 fps | 100% |
| Somchem S341 | <<locked>> | 86% | 54,940 psi | 89% | 2425 fps | 100% |
| Somchem S355 | <<locked>> | 94% | 55,767 psi | 90% | 2451 fps | 100% |
| Somchem S365ᴾ | <<locked>> | 100% | 50,053 psi | 81% | 2467 fps | 100% |
| Somchem S385ᴾ | <<locked>> | 100% | 46,789 psi | 75% | 2365 fps | 96.3% |
| Vihtavuori N130 | <<locked>> | 82% | 54,143 psi | 87% | 2293 fps | 100% |
| Vihtavuori N133 | <<locked>> | 86% | 54,679 psi | 88% | 2313 fps | 100% |
| Vihtavuori N135 | <<locked>> | 88% | 53,200 psi | 86% | 2352 fps | 100% |
| Vihtavuori N140 | <<locked>> | 88% | 53,998 psi | 87% | 2365 fps | 100% |
| Vihtavuori N150 | <<locked>> | 94% | 53,809 psi | 87% | 2392 fps | 100% |
| Vihtavuori N160 | <<locked>> | 98% | 54,839 psi | 88% | 2461 fps | 99.8% |
| Vihtavuori N530 | <<locked>> | 84% | 53,432 psi | 86% | 2385 fps | 100% |
| Vihtavuori N540 | <<locked>> | 90% | 55,463 psi | 89% | 2405 fps | 100% |
| Vihtavuori N550 | <<locked>> | 98% | 53,766 psi | 87% | 2467 fps | 99.6% |
| Vihtavuori N555ᴾ | <<locked>> | 100% | 42,525 psi | 69% | 2365 fps | 99.1% |
| Winchester 6.5 StaBALL | <<locked>> | 98% | 55,187 psi | 89% | 2444 fps | 100% |
| Winchester 748 | <<locked>> | 84% | 53,316 psi | 86% | 2428 fps | 100% |
| Winchester 760 | <<locked>> | 96% | 52,721 psi | 85% | 2477 fps | 98.1% |
| Winchester StaBALL HDᴾ | <<locked>> | 100% | 34,795 psi | 56% | 2306 fps | 99.2% |
| Winchester StaBALL Match | <<locked>> | 88% | 55,767 psi | 90% | 2454 fps | 100% |
Recommended = one of the top powders for this cartridge and bullet combination.
Start Load - Barrel Length: 23"
| Powder | Charge | FR | MaxP | % | V(0) | z |
|---|---|---|---|---|---|---|
| Accurate 2015 | <<locked>> | 80% | 48,762 psi | 79% | 2264 fps | 100% |
| Accurate 2495 | <<locked>> | 80% | 41,423 psi | 67% | 2205 fps | 100% |
| Accurate 2520 | <<locked>> | 80% | 48,312 psi | 78% | 2329 fps | 100% |
| Accurate 2700 | <<locked>> | 82% | 43,410 psi | 70% | 2221 fps | 95% |
| Accurate 3100 | <<locked>> | 98% | 37,884 psi | 61% | 2228 fps | 95.6% |
| Accurate 4064 | <<locked>> | 80% | 39,160 psi | 63% | 2201 fps | 100% |
| Accurate 4350 | <<locked>> | 84% | 32,721 psi | 53% | 2142 fps | 95.8% |
| ADI AR 2206H | <<locked>> | 80% | 44,802 psi | 72% | 2297 fps | 99.5% |
| ADI AR 2208 | <<locked>> | 80% | 38,116 psi | 61% | 2172 fps | 97.9% |
| ADI Benchmark 8208 | <<locked>> | 80% | 46,905 psi | 76% | 2303 fps | 100% |
| Alliant AR-Comp | <<locked>> | 80% | 47,253 psi | 76% | 2283 fps | 100% |
| Alliant Power Pro 2000-MR | 64.9 gr | 80% | 40,756 psi | 66% | 2329 fps | 98.5% |
| Alliant Reloder- TS 15.5 | <<locked>> | 80% | 37,782 psi | 61% | 2192 fps | 99.1% |
| Alliant Reloder-15 | <<locked>> | 80% | 40,553 psi | 65% | 2244 fps | 98.6% |
| Alliant Reloder-16 | <<locked>> | 82% | 31,270 psi | 50% | 2110 fps | 95% |
| Alliant Reloder-17 | 63.9 gr | 80% | 32,576 psi | 52% | 2169 fps | 97.6% |
| Alliant Reloder-23 | <<locked>> | 90% | 28,689 psi | 46% | 2073 fps | 95.7% |
| Alliant Reloder-26 | <<locked>> | 94% | 35,186 psi | 57% | 2277 fps | 96% |
| Baschieri & Pellagri 107 | <<locked>> | 80% | 43,932 psi | 71% | 2300 fps | 98.8% |
| Bofors RP3 | <<locked>> | 80% | 37,463 psi | 60% | 2198 fps | 99.1% |
| Bofors RP7 | <<locked>> | 88% | 43,584 psi | 70% | 2260 fps | 95.4% |
| Hodgdon Benchmark | <<locked>> | 80% | 48,660 psi | 78% | 2290 fps | 100% |
| Hodgdon BL-C2 | <<locked>> | 80% | 45,788 psi | 74% | 2323 fps | 100% |
| Hodgdon CFE223 | <<locked>> | 80% | 50,502 psi | 81% | 2448 fps | 99.8% |
| Hodgdon H380 | <<locked>> | 80% | 38,189 psi | 62% | 2195 fps | 96.9% |
| Hodgdon H414 | <<locked>> | 88% | 40,248 psi | 65% | 2280 fps | 95.2% |
| Hodgdon H4350 | <<locked>> | 90% | 47,079 psi | 76% | 2349 fps | 95.5% |
| Hodgdon H4895 | <<locked>> | 80% | 45,223 psi | 73% | 2306 fps | 99.8% |
| Hodgdon Hybrid 100V | <<locked>> | 80% | 26,890 psi | 43% | 1978 fps | 95% |
| Hodgdon LEVERevolution | <<locked>> | 80% | 41,162 psi | 66% | 2283 fps | 99.6% |
| Hodgdon Superformance | 76 gr | 90% | 42,946 psi | 69% | 2346 fps | 95.3% |
| Hodgdon TrailBoss | <<locked>> | 80% | 26,426 psi | 43% | 1312 fps | 100% |
| Hodgdon VARGET | <<locked>> | 80% | 43,366 psi | 70% | 2267 fps | 99.6% |
| IMR 3031 | <<locked>> | 80% | 45,034 psi | 73% | 2300 fps | 100% |
| IMR 4064 | <<locked>> | 80% | 40,016 psi | 64% | 2198 fps | 98.5% |
| IMR 4166 Enduron | <<locked>> | 80% | 42,511 psi | 68% | 2215 fps | 95.7% |
| IMR 4350 | <<locked>> | 92% | 43,685 psi | 70% | 2283 fps | 95.4% |
| IMR 4451 Enduron | <<locked>> | 86% | 42,540 psi | 69% | 2244 fps | 95.6% |
| IMR 4831 | <<locked>> | 84% | 31,850 psi | 51% | 2110 fps | 95.5% |
| IMR 4895 | <<locked>> | 80% | 41,524 psi | 67% | 2270 fps | 99.2% |
| IMR 8208 XBR | <<locked>> | 80% | 46,905 psi | 76% | 2303 fps | 100% |
| Lovex D073.6 | <<locked>> | 80% | 44,063 psi | 71% | 2280 fps | 100% |
| Lovex S060 | <<locked>> | 80% | 44,730 psi | 72% | 2241 fps | 99.5% |
| Lovex S062 | <<locked>> | 80% | 39,900 psi | 64% | 2201 fps | 99.6% |
| Lovex S065 | <<locked>> | 84% | 37,231 psi | 60% | 2156 fps | 95.7% |
| Lovex S070 | <<locked>> | 88% | 39,943 psi | 64% | 2224 fps | 95.3% |
| Norma 201 | <<locked>> | 80% | 43,990 psi | 71% | 2257 fps | 99.9% |
| Norma 202 | <<locked>> | 80% | 44,222 psi | 71% | 2260 fps | 100% |
| Norma 203B | <<locked>> | 80% | 39,900 psi | 64% | 2234 fps | 98.9% |
| Norma 204 | <<locked>> | 96% | 49,632 psi | 80% | 2408 fps | 95.5% |
| Norma URP | <<locked>> | 84% | 33,330 psi | 54% | 2149 fps | 95.8% |
| Ramshot Big Game | <<locked>> | 80% | 39,479 psi | 64% | 2247 fps | 98.7% |
| Ramshot Hunter | <<locked>> | 88% | 37,014 psi | 60% | 2224 fps | 95.1% |
| Ramshot TAC | <<locked>> | 80% | 46,804 psi | 75% | 2310 fps | 98.2% |
| Ramshot Wild Boar | <<locked>> | 80% | 46,354 psi | 75% | 2326 fps | 99.6% |
| Ramshot X-Terminator | <<locked>> | 80% | 50,502 psi | 81% | 2343 fps | 99.9% |
| ReloadSwiss RS 14 | <<locked>> | 80% | 26,774 psi | 43% | 1345 fps | 100% |
| ReloadSwiss RS 40 | <<locked>> | 80% | 52,504 psi | 85% | 2369 fps | 100% |
| ReloadSwiss RS 50 | <<locked>> | 80% | 38,725 psi | 62% | 2185 fps | 95.3% |
| ReloadSwiss RS 52 | <<locked>> | 80% | 42,685 psi | 69% | 2333 fps | 99% |
| ReloadSwiss RS 60 | <<locked>> | 80% | 34,708 psi | 56% | 2224 fps | 99.8% |
| ReloadSwiss RS 62 | <<locked>> | 84% | 32,576 psi | 52% | 2156 fps | 95.3% |
| ReloadSwiss RS 70 | <<locked>> | 86% | 35,012 psi | 56% | 2211 fps | 95.2% |
| Rottweil R 901 | <<locked>> | 80% | 48,022 psi | 77% | 2287 fps | 100% |
| Rottweil R 902 | <<locked>> | 80% | 41,814 psi | 67% | 2215 fps | 99.7% |
| Rottweil R 903 | <<locked>> | 80% | 35,157 psi | 57% | 2146 fps | 98.5% |
| Rottweil R 907 | <<locked>> | 88% | 43,584 psi | 70% | 2260 fps | 95.4% |
| Shooters World Long Rifle | <<locked>> | 84% | 37,231 psi | 60% | 2156 fps | 95.7% |
| Shooters World Match Rifle | <<locked>> | 80% | 44,063 psi | 71% | 2280 fps | 100% |
| Shooters World Precision | <<locked>> | 80% | 39,900 psi | 64% | 2201 fps | 99.6% |
| Shooters World SW4350 | <<locked>> | 88% | 39,943 psi | 64% | 2224 fps | 95.3% |
| SNPE Vectan SP 11 | <<locked>> | 80% | 36,143 psi | 58% | 2192 fps | 98% |
| SNPE Vectan SP 7 | <<locked>> | 80% | 45,049 psi | 73% | 2287 fps | 98.4% |
| SNPE Vectan SP 9 | <<locked>> | 80% | 43,294 psi | 70% | 2274 fps | 99.3% |
| SNPE Vectan Tubal 3000 | <<locked>> | 80% | 45,295 psi | 73% | 2211 fps | 100% |
| SNPE Vectan Tubal 5000 | <<locked>> | 80% | 37,681 psi | 61% | 2100 fps | 100% |
| SNPE Vectan Tubal 7000 | <<locked>> | 88% | 41,423 psi | 67% | 2195 fps | 95.5% |
| Somchem S321 | <<locked>> | 80% | 50,647 psi | 82% | 2369 fps | 100% |
| Somchem S335 | <<locked>> | 80% | 44,904 psi | 72% | 2215 fps | 100% |
| Somchem S341 | <<locked>> | 80% | 44,715 psi | 72% | 2283 fps | 99.5% |
| Somchem S355 | <<locked>> | 80% | 36,085 psi | 58% | 2152 fps | 98.5% |
| Somchem S365 | <<locked>> | 80% | 26,194 psi | 42% | 2011 fps | 96.3% |
| Somchem S385 | <<locked>> | 98% | 43,685 psi | 70% | 2316 fps | 95.5% |
| Vihtavuori N130 | <<locked>> | 80% | 51,053 psi | 82% | 2257 fps | 100% |
| Vihtavuori N133 | <<locked>> | 80% | 45,614 psi | 73% | 2205 fps | 100% |
| Vihtavuori N135 | <<locked>> | 80% | 41,336 psi | 67% | 2198 fps | 100% |
| Vihtavuori N140 | <<locked>> | 80% | 41,814 psi | 67% | 2205 fps | 100% |
| Vihtavuori N150 | <<locked>> | 80% | 34,200 psi | 55% | 2096 fps | 99.1% |
| Vihtavuori N160 | <<locked>> | 82% | 32,503 psi | 52% | 2100 fps | 95.4% |
| Vihtavuori N530 | <<locked>> | 80% | 47,050 psi | 76% | 2300 fps | 100% |
| Vihtavuori N540 | <<locked>> | 80% | 40,292 psi | 65% | 2198 fps | 100% |
| Vihtavuori N550 | <<locked>> | 82% | 31,995 psi | 52% | 2103 fps | 95% |
| Vihtavuori N555 | <<locked>> | 90% | 30,777 psi | 50% | 2139 fps | 95.8% |
| Winchester 6.5 StaBALL | <<locked>> | 80% | 30,342 psi | 49% | 2034 fps | 96.8% |
| Winchester 748 | <<locked>> | 80% | 46,557 psi | 75% | 2336 fps | 100% |
| Winchester 760 | <<locked>> | 88% | 40,422 psi | 65% | 2283 fps | 95.3% |
| Winchester StaBALL HD | <<locked>> | 94% | 28,790 psi | 46% | 2142 fps | 96.3% |
| Winchester StaBALL Match | <<locked>> | 80% | 42,728 psi | 69% | 2277 fps | 99.6% |
Recommended = one of the top powders for this cartridge and bullet combination.
ᴾ possible press load - work up slowly to this load while watching for signs of excessive pressure.
This overview compares 98 powders for .375 Ruger loaded with the .375 | 300gr | Hornady InterBond RN. Alliant Reloder-17 delivers the highest muzzle velocity at 2,556 fps; across all powders the maximum-charge window runs from 1,473 fps to 2,556 fps. Accurate 3100 gives the best case fill at 100 %, and 98 of the 98 powders fall inside the usable 80–100 % fill window.
Relative to the caliber's maximum pressure (428 MPa), the top charges use 56–90 %, leaving at least 10 % headroom. The 300.0 gr projectile in 0.375" calls for a 1:6.0 twist; slower twists will usually not stabilise this weight. Accurate 3100, Alliant Reloder-16, Alliant Reloder-23 reach 100 % fill or more at maximum charge, so these are compressed loads: they need a long drop tube to seat cleanly and react sensitively to the case capacity of your own brass lot. Alliant Power Pro 2000-MR, Hodgdon Superformance, Alliant Reloder-17 rank at the top here: for .375 Ruger with the .375 | 300gr | Hornady InterBond RN they combine a high case fill with complete burn and sit in the upper velocity band. Always begin at the start load and work up in small increments while checking case and primer for pressure signs.