
Load Specifications
Load data in caliber .375 Ruger with .375 | 270gr | Hornady InterLock RN bullet and 98 powders. The key underlying parameters are shown in the table above. The recommended powders for this cartridge and bullet combination are Alliant Power Pro 2000-MR, ReloadSwiss RS 60 and Hodgdon Superformance.
Important Notice: DO NOT go below Minimum Charge or above Maximum Charge. Since we have no control over the equipment and components used, any responsibility and liability for the results achieved is rejected.
Only powders/loads that match the current filter criteria are displayed: max pressure of a load ≤ 90% of max. standardized pressure, fill rate ≥ 80% and propellant combustion ≥ 95%. Use the sliders above the tables to adjust these thresholds.
Charge: Powder weight in grains. Start with the minimum load and work up carefully.
FR (Fill Rate): Case fill as a percentage. Values above 100% mean compressed loads.
MaxP / %: Maximum chamber pressure in bar and as a percentage of the standardized maximum for this caliber.
V(0): Muzzle velocity in feet per second (fps) at the standardized barrel length.
z (Powder Burn): Estimated propellant combustion percentage at bullet exit.
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You can find more information in our FAQ: How can I use the Personalized Load Calculator?
Max Load - Barrel Length: 23"
| Powder | Charge | FR | MaxP | % | V(0) | z |
|---|---|---|---|---|---|---|
| Accurate 2015 | <<locked>> | 84% | 54,302 psi | 87% | 2480 fps | 100% |
| Accurate 2460 | <<locked>> | 82% | 56,014 psi | 90% | 2543 fps | 100% |
| Accurate 2495 | <<locked>> | 88% | 52,663 psi | 85% | 2497 fps | 100% |
| Accurate 2520 | <<locked>> | 84% | 54,636 psi | 88% | 2559 fps | 100% |
| Accurate 2700 | <<locked>> | 90% | 55,579 psi | 90% | 2539 fps | 97% |
| Accurate 4064 | <<locked>> | 92% | 56,130 psi | 90% | 2582 fps | 100% |
| Accurate 4350ᴾ | <<locked>> | 100% | 56,072 psi | 90% | 2657 fps | 99.7% |
| ADI AR 2206H | <<locked>> | 86% | 53,374 psi | 86% | 2569 fps | 99.9% |
| ADI AR 2208 | <<locked>> | 92% | 54,418 psi | 88% | 2569 fps | 99.7% |
| ADI Benchmark 8208 | <<locked>> | 86% | 55,825 psi | 90% | 2569 fps | 100% |
| Alliant AR-Comp | <<locked>> | 84% | 52,982 psi | 85% | 2503 fps | 100% |
| Alliant Power Pro 2000-MR | <<locked>> | 88% | 52,765 psi | 85% | 2671 fps | 99.7% |
| Alliant Reloder- TS 15.5 | <<locked>> | 92% | 54,143 psi | 87% | 2585 fps | 100% |
| Alliant Reloder-15 | <<locked>> | 90% | 54,752 psi | 88% | 2605 fps | 99.8% |
| Alliant Reloder-16ᴾ | <<locked>> | 100% | 53,577 psi | 86% | 2657 fps | 99.7% |
| Alliant Reloder-17 | <<locked>> | 96% | 54,853 psi | 88% | 2694 fps | 100% |
| Alliant Reloder-23ᴾ | <<locked>> | 100% | 38,348 psi | 62% | 2418 fps | 98.5% |
| Alliant Reloder-26ᴾ | <<locked>> | 100% | 42,772 psi | 69% | 2559 fps | 97.7% |
| Baschieri & Pellagri 107 | <<locked>> | 86% | 52,997 psi | 85% | 2579 fps | 99.5% |
| Bofors RP3 | <<locked>> | 92% | 54,882 psi | 88% | 2602 fps | 100% |
| Bofors RP7 | <<locked>> | 96% | 55,085 psi | 89% | 2572 fps | 97.2% |
| Hodgdon Benchmark | <<locked>> | 84% | 54,157 psi | 87% | 2510 fps | 100% |
| Hodgdon BL-C2 | <<locked>> | 86% | 55,056 psi | 89% | 2595 fps | 100% |
| Hodgdon CFE223 | <<locked>> | 82% | 53,258 psi | 86% | 2635 fps | 99.8% |
| Hodgdon H380 | <<locked>> | 92% | 55,898 psi | 90% | 2612 fps | 99.4% |
| Hodgdon H414 | <<locked>> | 98% | 55,172 psi | 89% | 2651 fps | 97.9% |
| Hodgdon H4350 | <<locked>> | 96% | 56,115 psi | 90% | 2621 fps | 96.8% |
| Hodgdon H4895 | <<locked>> | 86% | 53,954 psi | 87% | 2579 fps | 100% |
| Hodgdon Hybrid 100Vᴾ | <<locked>> | 100% | 49,850 psi | 80% | 2546 fps | 99.9% |
| Hodgdon LEVERevolution | <<locked>> | 88% | 53,113 psi | 86% | 2605 fps | 100% |
| Hodgdon Superformance | <<locked>> | 96% | 52,272 psi | 84% | 2631 fps | 96.9% |
| Hodgdon TrailBossᴾ | <<locked>> | 100% | 35,462 psi | 57% | 1578 fps | 100% |
| Hodgdon VARGET | <<locked>> | 88% | 55,129 psi | 89% | 2579 fps | 100% |
| IMR 3031 | <<locked>> | 86% | 53,664 psi | 86% | 2562 fps | 100% |
| IMR 4064 | <<locked>> | 90% | 53,882 psi | 87% | 2552 fps | 99.8% |
| IMR 4166 Enduron | <<locked>> | 88% | 53,867 psi | 87% | 2530 fps | 97.5% |
| IMR 4350ᴾ | <<locked>> | 100% | 55,085 psi | 89% | 2592 fps | 97.3% |
| IMR 4451 Enduron | <<locked>> | 94% | 53,650 psi | 86% | 2552 fps | 97.4% |
| IMR 4831ᴾ | <<locked>> | 100% | 52,779 psi | 85% | 2602 fps | 99.5% |
| IMR 4895 | <<locked>> | 90% | 56,144 psi | 90% | 2631 fps | 100% |
| IMR 8208 XBR | <<locked>> | 86% | 55,825 psi | 90% | 2569 fps | 100% |
| Lovex D073.5 | <<locked>> | 82% | 56,072 psi | 90% | 2556 fps | 100% |
| Lovex D073.6 | <<locked>> | 86% | 52,939 psi | 85% | 2546 fps | 100% |
| Lovex S060 | <<locked>> | 86% | 53,098 psi | 86% | 2503 fps | 99.9% |
| Lovex S062 | <<locked>> | 90% | 53,519 psi | 86% | 2549 fps | 100% |
| Lovex S065 | <<locked>> | 98% | 56,144 psi | 90% | 2592 fps | 98.9% |
| Lovex S070 | <<locked>> | 98% | 53,722 psi | 87% | 2575 fps | 97.8% |
| Norma 201 | <<locked>> | 88% | 55,405 psi | 89% | 2562 fps | 100% |
| Norma 202 | <<locked>> | 88% | 55,927 psi | 90% | 2566 fps | 100% |
| Norma 203B | <<locked>> | 90% | 53,998 psi | 87% | 2592 fps | 99.9% |
| Norma 204ᴾ | <<locked>> | 100% | 55,825 psi | 90% | 2635 fps | 96.1% |
| Norma URPᴾ | <<locked>> | 100% | 54,955 psi | 89% | 2644 fps | 99.6% |
| Ramshot Big Game | <<locked>> | 90% | 54,520 psi | 88% | 2615 fps | 99.9% |
| Ramshot Hunterᴾ | <<locked>> | 100% | 53,708 psi | 87% | 2641 fps | 98.4% |
| Ramshot TAC | <<locked>> | 84% | 52,605 psi | 85% | 2536 fps | 98.6% |
| Ramshot Wild Boar | <<locked>> | 86% | 55,753 psi | 90% | 2605 fps | 100% |
| Ramshot X-Terminator | <<locked>> | 82% | 53,171 psi | 86% | 2523 fps | 99.8% |
| ReloadSwiss RS 14ᴾ | <<locked>> | 100% | 35,868 psi | 58% | 1614 fps | 100% |
| ReloadSwiss RS 40 | <<locked>> | 82% | 55,172 psi | 89% | 2549 fps | 100% |
| ReloadSwiss RS 50 | <<locked>> | 90% | 52,707 psi | 85% | 2546 fps | 97.9% |
| ReloadSwiss RS 52 | <<locked>> | 88% | 55,129 psi | 89% | 2664 fps | 99.9% |
| ReloadSwiss RS 60 | <<locked>> | 94% | 54,650 psi | 88% | 2694 fps | 100% |
| ReloadSwiss RS 62ᴾ | <<locked>> | 100% | 55,738 psi | 90% | 2677 fps | 99.6% |
| ReloadSwiss RS 70ᴾ | <<locked>> | 100% | 55,492 psi | 89% | 2703 fps | 99.4% |
| Rottweil R 901 | <<locked>> | 84% | 53,156 psi | 86% | 2503 fps | 100% |
| Rottweil R 902 | <<locked>> | 90% | 55,956 psi | 90% | 2562 fps | 100% |
| Rottweil R 903 | <<locked>> | 94% | 54,752 psi | 88% | 2592 fps | 100% |
| Rottweil R 907 | <<locked>> | 96% | 55,085 psi | 89% | 2572 fps | 97.2% |
| Shooters World Long Rifle | <<locked>> | 98% | 56,144 psi | 90% | 2592 fps | 98.9% |
| Shooters World Match Rifle | <<locked>> | 86% | 52,939 psi | 85% | 2546 fps | 100% |
| Shooters World Precision | <<locked>> | 90% | 53,519 psi | 86% | 2549 fps | 100% |
| Shooters World SW4350 | <<locked>> | 98% | 53,722 psi | 87% | 2575 fps | 97.8% |
| SNPE Vectan SP 11 | <<locked>> | 92% | 52,837 psi | 85% | 2598 fps | 99.9% |
| SNPE Vectan SP 7 | <<locked>> | 86% | 54,592 psi | 88% | 2566 fps | 99.2% |
| SNPE Vectan SP 9 | <<locked>> | 88% | 55,085 psi | 89% | 2585 fps | 99.9% |
| SNPE Vectan Tubal 3000 | <<locked>> | 86% | 53,795 psi | 87% | 2467 fps | 100% |
| SNPE Vectan Tubal 5000 | <<locked>> | 92% | 53,853 psi | 87% | 2464 fps | 100% |
| SNPE Vectan Tubal 7000 | <<locked>> | 96% | 53,171 psi | 86% | 2503 fps | 97.4% |
| Somchem S321 | <<locked>> | 82% | 53,432 psi | 86% | 2552 fps | 100% |
| Somchem S335 | <<locked>> | 86% | 52,997 psi | 85% | 2464 fps | 100% |
| Somchem S341 | <<locked>> | 86% | 54,085 psi | 87% | 2556 fps | 99.9% |
| Somchem S355 | <<locked>> | 94% | 54,926 psi | 88% | 2589 fps | 100% |
| Somchem S365ᴾ | <<locked>> | 100% | 49,255 psi | 79% | 2598 fps | 100% |
| Vihtavuori N130 | <<locked>> | 82% | 53,519 psi | 86% | 2434 fps | 100% |
| Vihtavuori N133 | <<locked>> | 86% | 54,012 psi | 87% | 2454 fps | 100% |
| Vihtavuori N135 | <<locked>> | 90% | 55,506 psi | 89% | 2526 fps | 100% |
| Vihtavuori N140 | <<locked>> | 88% | 53,084 psi | 86% | 2503 fps | 100% |
| Vihtavuori N150 | <<locked>> | 94% | 53,098 psi | 86% | 2526 fps | 100% |
| Vihtavuori N160 | <<locked>> | 98% | 53,896 psi | 87% | 2592 fps | 99.4% |
| Vihtavuori N530 | <<locked>> | 84% | 52,794 psi | 85% | 2523 fps | 100% |
| Vihtavuori N540 | <<locked>> | 90% | 54,679 psi | 88% | 2543 fps | 100% |
| Vihtavuori N550 | <<locked>> | 98% | 53,069 psi | 85% | 2602 fps | 99.3% |
| Vihtavuori N555ᴾ | <<locked>> | 100% | 41,800 psi | 67% | 2490 fps | 98.4% |
| Winchester 6.5 StaBALL | <<locked>> | 98% | 54,462 psi | 88% | 2575 fps | 100% |
| Winchester 748 | <<locked>> | 86% | 56,115 psi | 90% | 2612 fps | 100% |
| Winchester 760 | <<locked>> | 98% | 55,448 psi | 89% | 2657 fps | 98% |
| Winchester StaBALL HDᴾ | <<locked>> | 100% | 34,287 psi | 55% | 2411 fps | 98.2% |
| Winchester StaBALL Match | <<locked>> | 88% | 55,042 psi | 89% | 2595 fps | 100% |
Recommended = one of the top powders for this cartridge and bullet combination.
Start Load - Barrel Length: 23"
| Powder | Charge | FR | MaxP | % | V(0) | z |
|---|---|---|---|---|---|---|
| Accurate 2015 | <<locked>> | 80% | 47,848 psi | 77% | 2395 fps | 100% |
| Accurate 2460 | <<locked>> | 80% | 52,402 psi | 84% | 2497 fps | 100% |
| Accurate 2495 | <<locked>> | 80% | 40,712 psi | 66% | 2333 fps | 100% |
| Accurate 2520 | <<locked>> | 80% | 47,500 psi | 77% | 2464 fps | 100% |
| Accurate 2700 | <<locked>> | 86% | 48,762 psi | 79% | 2441 fps | 95.6% |
| Accurate 4064 | <<locked>> | 80% | 38,464 psi | 62% | 2326 fps | 100% |
| Accurate 4350 | <<locked>> | 86% | 34,490 psi | 56% | 2306 fps | 95.6% |
| ADI AR 2206H | <<locked>> | 80% | 44,179 psi | 71% | 2425 fps | 99.1% |
| ADI AR 2208 | <<locked>> | 80% | 37,579 psi | 61% | 2290 fps | 97.1% |
| ADI Benchmark 8208 | <<locked>> | 80% | 46,209 psi | 74% | 2434 fps | 99.8% |
| Alliant AR-Comp | <<locked>> | 80% | 46,485 psi | 75% | 2421 fps | 100% |
| Alliant Power Pro 2000-MR | 69.4 gr | 80% | 40,001 psi | 64% | 2448 fps | 97.6% |
| Alliant Reloder- TS 15.5 | <<locked>> | 80% | 37,115 psi | 60% | 2310 fps | 98.5% |
| Alliant Reloder-15 | <<locked>> | 80% | 39,929 psi | 64% | 2369 fps | 97.9% |
| Alliant Reloder-16 | <<locked>> | 86% | 34,737 psi | 56% | 2313 fps | 95.6% |
| Alliant Reloder-17 | <<locked>> | 80% | 32,068 psi | 52% | 2277 fps | 96.4% |
| Alliant Reloder-23 | <<locked>> | 92% | 29,994 psi | 48% | 2224 fps | 95.2% |
| Alliant Reloder-26 | <<locked>> | 96% | 37,159 psi | 60% | 2444 fps | 95.8% |
| Baschieri & Pellagri 107 | <<locked>> | 80% | 43,250 psi | 70% | 2425 fps | 98.1% |
| Bofors RP3 | <<locked>> | 80% | 36,753 psi | 59% | 2313 fps | 98.5% |
| Bofors RP7 | <<locked>> | 90% | 45,672 psi | 74% | 2428 fps | 95.1% |
| Hodgdon Benchmark | <<locked>> | 80% | 47,964 psi | 77% | 2425 fps | 100% |
| Hodgdon BL-C2 | <<locked>> | 80% | 44,976 psi | 72% | 2451 fps | 99.9% |
| Hodgdon CFE223 | <<locked>> | 80% | 49,734 psi | 80% | 2582 fps | 99.5% |
| Hodgdon H380 | <<locked>> | 80% | 37,579 psi | 61% | 2313 fps | 95.9% |
| Hodgdon H414 | <<locked>> | 90% | 42,308 psi | 68% | 2448 fps | 95% |
| Hodgdon H4350 | <<locked>> | 92% | 49,400 psi | 80% | 2523 fps | 95.3% |
| Hodgdon H4895 | <<locked>> | 80% | 44,585 psi | 72% | 2434 fps | 99.4% |
| Hodgdon Hybrid 100V | <<locked>> | 84% | 29,950 psi | 48% | 2175 fps | 95.6% |
| Hodgdon LEVERevolution | <<locked>> | 80% | 40,509 psi | 65% | 2408 fps | 99.2% |
| Hodgdon Superformance | 83.1 gr | 92% | 45,339 psi | 73% | 2520 fps | 95.1% |
| Hodgdon TrailBoss | <<locked>> | 80% | 26,397 psi | 43% | 1411 fps | 100% |
| Hodgdon VARGET | <<locked>> | 80% | 42,801 psi | 69% | 2392 fps | 99.2% |
| IMR 3031 | <<locked>> | 80% | 44,164 psi | 71% | 2431 fps | 100% |
| IMR 4064 | <<locked>> | 80% | 39,450 psi | 64% | 2320 fps | 97.8% |
| IMR 4166 Enduron | <<locked>> | 82% | 44,701 psi | 72% | 2385 fps | 95.5% |
| IMR 4350 | <<locked>> | 94% | 45,759 psi | 74% | 2451 fps | 95.2% |
| IMR 4451 Enduron | <<locked>> | 88% | 44,498 psi | 72% | 2411 fps | 95.3% |
| IMR 4831 | <<locked>> | 86% | 33,388 psi | 54% | 2264 fps | 95.2% |
| IMR 4895 | <<locked>> | 80% | 40,857 psi | 66% | 2395 fps | 98.6% |
| IMR 8208 XBR | <<locked>> | 80% | 46,209 psi | 74% | 2434 fps | 99.8% |
| Lovex D073.5 | <<locked>> | 80% | 52,286 psi | 84% | 2507 fps | 100% |
| Lovex D073.6 | <<locked>> | 80% | 43,308 psi | 70% | 2408 fps | 100% |
| Lovex S060 | <<locked>> | 80% | 44,208 psi | 71% | 2369 fps | 99.1% |
| Lovex S062 | <<locked>> | 80% | 39,320 psi | 63% | 2326 fps | 99.2% |
| Lovex S065 | <<locked>> | 86% | 38,841 psi | 63% | 2316 fps | 95.3% |
| Lovex S070 | <<locked>> | 90% | 41,756 psi | 67% | 2385 fps | 95% |
| Norma 201 | <<locked>> | 80% | 43,323 psi | 70% | 2385 fps | 99.6% |
| Norma 202 | <<locked>> | 80% | 43,497 psi | 70% | 2392 fps | 100% |
| Norma 203B | <<locked>> | 80% | 39,291 psi | 63% | 2356 fps | 98.2% |
| Norma 204 | <<locked>> | 98% | 52,141 psi | 84% | 2582 fps | 95.3% |
| Norma URP | <<locked>> | 86% | 34,809 psi | 56% | 2306 fps | 95.5% |
| Ramshot Big Game | <<locked>> | 80% | 38,696 psi | 62% | 2365 fps | 97.9% |
| Ramshot Hunter | <<locked>> | 92% | 41,408 psi | 67% | 2441 fps | 95.7% |
| Ramshot TAC | <<locked>> | 80% | 46,180 psi | 74% | 2438 fps | 97.5% |
| Ramshot Wild Boar | <<locked>> | 80% | 45,527 psi | 73% | 2454 fps | 99.2% |
| Ramshot X-Terminator | <<locked>> | 80% | 49,893 psi | 80% | 2477 fps | 99.6% |
| ReloadSwiss RS 14 | <<locked>> | 80% | 26,687 psi | 43% | 1444 fps | 100% |
| ReloadSwiss RS 40 | <<locked>> | 80% | 51,851 psi | 84% | 2507 fps | 100% |
| ReloadSwiss RS 50 | <<locked>> | 82% | 40,611 psi | 65% | 2349 fps | 95% |
| ReloadSwiss RS 52 | <<locked>> | 80% | 41,800 psi | 67% | 2457 fps | 98.3% |
| ReloadSwiss RS 60 | 68.4 gr | 80% | 34,127 psi | 55% | 2339 fps | 99.3% |
| ReloadSwiss RS 62 | <<locked>> | 86% | 34,229 psi | 55% | 2316 fps | 95% |
| ReloadSwiss RS 70 | <<locked>> | 88% | 36,956 psi | 60% | 2375 fps | 95% |
| Rottweil R 901 | <<locked>> | 80% | 47,181 psi | 76% | 2421 fps | 100% |
| Rottweil R 902 | <<locked>> | 80% | 41,089 psi | 66% | 2339 fps | 99.4% |
| Rottweil R 903 | <<locked>> | 80% | 34,606 psi | 56% | 2264 fps | 97.7% |
| Rottweil R 907 | <<locked>> | 90% | 45,672 psi | 74% | 2428 fps | 95.1% |
| Shooters World Long Rifle | <<locked>> | 86% | 38,841 psi | 63% | 2316 fps | 95.3% |
| Shooters World Match Rifle | <<locked>> | 80% | 43,308 psi | 70% | 2408 fps | 100% |
| Shooters World Precision | <<locked>> | 80% | 39,320 psi | 63% | 2326 fps | 99.2% |
| Shooters World SW4350 | <<locked>> | 90% | 41,756 psi | 67% | 2385 fps | 95% |
| SNPE Vectan SP 11 | <<locked>> | 80% | 35,476 psi | 57% | 2306 fps | 97.1% |
| SNPE Vectan SP 7 | <<locked>> | 80% | 44,338 psi | 71% | 2411 fps | 97.6% |
| SNPE Vectan SP 9 | <<locked>> | 80% | 42,641 psi | 69% | 2395 fps | 98.8% |
| SNPE Vectan Tubal 3000 | <<locked>> | 80% | 44,541 psi | 72% | 2339 fps | 100% |
| SNPE Vectan Tubal 5000 | <<locked>> | 80% | 37,028 psi | 60% | 2221 fps | 100% |
| SNPE Vectan Tubal 7000 | <<locked>> | 90% | 43,700 psi | 70% | 2359 fps | 95.3% |
| Somchem S321 | <<locked>> | 80% | 49,922 psi | 80% | 2503 fps | 100% |
| Somchem S335 | <<locked>> | 80% | 44,280 psi | 71% | 2343 fps | 100% |
| Somchem S341 | <<locked>> | 80% | 44,019 psi | 71% | 2408 fps | 99% |
| Somchem S355 | <<locked>> | 80% | 35,491 psi | 57% | 2270 fps | 97.7% |
| Somchem S365 | <<locked>> | 82% | 27,340 psi | 44% | 2159 fps | 95.9% |
| Vihtavuori N130 | <<locked>> | 80% | 50,270 psi | 81% | 2395 fps | 100% |
| Vihtavuori N133 | <<locked>> | 80% | 44,860 psi | 72% | 2333 fps | 100% |
| Vihtavuori N135 | <<locked>> | 80% | 40,495 psi | 65% | 2323 fps | 100% |
| Vihtavuori N140 | <<locked>> | 80% | 41,249 psi | 66% | 2333 fps | 100% |
| Vihtavuori N150 | <<locked>> | 80% | 33,721 psi | 54% | 2211 fps | 98.4% |
| Vihtavuori N160 | <<locked>> | 84% | 34,069 psi | 55% | 2257 fps | 95.1% |
| Vihtavuori N530 | <<locked>> | 80% | 46,340 psi | 75% | 2431 fps | 99.9% |
| Vihtavuori N540 | <<locked>> | 80% | 39,711 psi | 64% | 2323 fps | 100% |
| Vihtavuori N550 | <<locked>> | 86% | 35,868 psi | 58% | 2310 fps | 95.6% |
| Vihtavuori N555 | <<locked>> | 92% | 32,169 psi | 52% | 2293 fps | 95.4% |
| Winchester 6.5 StaBALL | <<locked>> | 80% | 29,892 psi | 48% | 2139 fps | 95.6% |
| Winchester 748 | <<locked>> | 80% | 45,861 psi | 74% | 2470 fps | 100% |
| Winchester 760 | <<locked>> | 90% | 42,467 psi | 68% | 2451 fps | 95% |
| Winchester StaBALL HD | <<locked>> | 96% | 30,197 psi | 49% | 2297 fps | 95.9% |
| Winchester StaBALL Match | <<locked>> | 80% | 42,076 psi | 68% | 2402 fps | 99.1% |
Recommended = one of the top powders for this cartridge and bullet combination.
ᴾ possible press load - work up slowly to this load while watching for signs of excessive pressure.
This overview compares 98 powders for .375 Ruger loaded with the .375 | 270gr | Hornady InterLock RN. ReloadSwiss RS 70 delivers the highest muzzle velocity at 2,703 fps; across all powders the maximum-charge window runs from 1,578 fps to 2,703 fps. Accurate 4350 gives the best case fill at 100 %, and 98 of the 98 powders fall inside the usable 80–100 % fill window.
Relative to the caliber's maximum pressure (428 MPa), the top charges use 55–90 %, leaving at least 10 % headroom. Accurate 4350, Alliant Reloder-16, Alliant Reloder-23 reach 100 % fill or more at maximum charge, so these are compressed loads: they need a long drop tube to seat cleanly and react sensitively to the case capacity of your own brass lot. Alliant Power Pro 2000-MR, ReloadSwiss RS 60, Hodgdon Superformance rank at the top here: for .375 Ruger with the .375 | 270gr | Hornady InterLock RN they combine a high case fill with complete burn and sit in the upper velocity band. Always begin at the start load and work up in small increments while checking case and primer for pressure signs.